Host institution: National Medical Research Institute, Korogwe, Tanzania; Prof John Lusingu and Dr Daniel Minja
Supervisor: Assoc Prof Michael Alifrangis
Co Supevisors: Assist Prof Christentze Schmiegelow and Prof Thor Grundtvig
Study Title: The effect of malaria and sexually transmitted infections/reproductive tract infections during pregnancy on foetal growth, pregnancy outcomes and post-natal growth trajectories
The PhD hypothesis is that weight will reduce rapidly during the first days of life and will increase by the end of the first week of life but at a slower rate than observed in high income countries. It is also hypothesized that malaria in pregnancy (MIP) or sexually transmitted /reproductive tract infections (STIs/RTIs) will have detrimental effect on foetal growth, newborn anthropometrics, and post-natal growth. Furthermore, it is hypothesized that co-infections with MIP and STIs/RTIs may have synergistic or additive harmful effect on foetal growth, newborn anthropometrics, and post-natal growth.
To assess the daily change in weight during the first week of life among breastfed newborns in Tanzania.
To assess the effect of malaria in pregnancy on foetal growth trajectories, preterm delivery, and perinatal death.
To assess the effect of STIs/RTIs on foetal growth trajectories, preterm delivery, and perinatal death.
To assess if there is a synergistic or additive effect of malaria in pregnancy and STIs/RTIs on foetal growth, preterm delivery and perinatal death.
To assess the effect of malaria in pregnancy and STIs/RTIs on growth trajectories from birth to 6 weeks of age.